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. Author manuscript; available in PMC: 2021 Jan 18.
Published in final edited form as: Clin Genet. 2020 Mar 5;97(5):764–769. doi: 10.1111/cge.13722

Figure 3: Clinical and transcriptional phenotypes of dominant and recessive forms of nanophthalmos.

Figure 3:

Mean ocular axial length (A) and spherical equivalent (B) of affected individuals stratified by genetic diagnosis. For both phenotypes, group means were significantly different by one-way ANOVA (P<0.0005), with asterisks (*) indicating a significant difference from the unsolved cohort (Tukey multiple comparison testing, P<0.03). (C) Relative mean expression dendrogram (normalised log counts per kb per million mapped reads) of genes in dissected human adult cadaveric eye tissue. S, sclera; CS, corneal stroma; CE, corneal epithelium; TM, trabecular meshwork; DM, Descemet’s membrane; ON, optic nerve; ONH, optic nerve head; PI, peripheral iris; CB, ciliary body.