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TM4SF4 knockdown in lung adenocarcinoma cell lines reduces cell growth. A549 and Calu-3 are treated with lenti-shTM4SF4. (A) Growth curve shows the effect of targeting TM4SF4 in A549 and Calu-3 cells. (B, C) TM4SF4 knockdown is confirmed by quantitative reverse transcription–polymerase chain reaction and fluorescence-activated cell sorting analysis. Values represent mean±standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001.
