Table 4.

Multivariate COX regression analysis of factors associated with all-cause mortality in young (aged <50) compared with older (aged ≥50) patients with STEMI treated with PPCI

	Age <50		Age ≥50
	Adjusted HR (95% CI)	P value	Adjusted HR (95% CI)	P value
Age, per 1 year increase	0.93 (0.85–1.02)	0.134	1.05 (1.03–1.07)	<0.0001
Female gender	1.34 (0.29–7.97)	0.667	0.63 (0.41–0.97)	0.037
Indian ethnicity	0.83 (0.25–2.55)	0.756	1.47 (0.97–2.23)	0.070
Current smoker	0.74 (0.31–2.43)	0.567	0.78 (0.54–1.12)	0.185
Hypertension	0.61 (0.16–2.05)	0.467	1.01 (0.71–1.44)	0.939
Diabetes mellitus	2.77 (0.90–8.53)	0.077	1.31 (0.95–1.89)	0.102
Dyslipidaemia	0.46 (0.12–1.49)	0.235	1.02 (0.73–1.42)	0.911
Family history of IHD	0.20 (0.03–1.62)	0.133	0.60 (0.28–1.29)	0.191
Previous AMI	1.48 (0.24–8.33)	0.672	0.74 (0.48–1.14)	0.172
Previous stroke	19.17 (2.69–85.68)	0.003	1.24 (0.75–2.04)	0.409
Chronic kidney disease	0.05 (0.01–72.23)	0.987	2.58 (1.73–3.81)	<0.0001
Atrial fibrillation	0.05 (0.01–42.67)	0.997	1.18 (0.58–2.43)	0.649
DTBT ≥90 min	5.42 (1.97–14.93)	0.001	2.07 (1.51–2.84)	<0.0001
Multivessel disease	3.21 (1.13–9.08)	0.028	1.06 (0.78–1.43)	0.720

AMI, acute myocardial infarction; DTBT, door to balloon time; IHD, ischaemic heart disease; PPCI, primary percutaneous coronary intervention; STEMI, ST segment elevation myocardial infarction.