Table 4.
Characteristic | aHR (95% CI) | P value |
Timing of entering the cohort | ||
1991–1997 | Ref. | |
2000–2009 | 1.10 (1.01 to 1.21) | 0.025 |
2011–2015 | 1.19 (1.04 to 1.37) | 0.010 |
Geographic region | ||
Western | Ref. | |
Central | 1.26 (1.16 to 1.37) | <0.001 |
Northeastern | 1.56 (1.41 to 1.72) | <0.001 |
Eastern | 1.48 (1.36 to 1.63) | <0.001 |
Urban (vs rural) | 0.94 (0.88 to 1.01) | 0.109 |
Age* | ||
18–29 | Ref. | |
30–39 | 1.93 (1.41 to 2.65) | <0.001 |
40–49 | 3.99 (2.93 to 5.43) | <0.001 |
50–59 | 5.16 (3.74 to 7.12) | <0.001 |
≥60 | 9.11 (6.50 to 12.77) | <0.001 |
Female (vs male) | 0.81 (0.74 to 0.88) | <0.001 |
Body mass index (kg/m2) | ||
<18.5 | Ref. | |
18.5–23.9 | 1.31 (1.16 to 1.48) | <0.001 |
24.0–27.9 | 2.07 (1.81 to 2.36) | <0.001 |
≥28 | 2.82 (2.37 to 3.34) | <0.001 |
Race (Han vs others) | 1.11 (1.01 to 1.23) | 0.032 |
Married (vs others) | 0.92 (0.83 to 1.02) | 0.149 |
Educational attainment | ||
Primary school and below | Ref. | |
Middle school | 0.91 (0.84 to 0.99) | 0.020 |
High school or equivalent | 0.86 (0.77 to 0.95) | 0.002 |
College and above | 0.82 (0.68 to 0.98) | 0.033 |
Employed (yes vs no) | 0.90 (0.82 to 0.99) | 0.036 |
Smoking | ||
Never or smoking cessation | Ref. | |
Current smoker, cigarettes <20/day | 0.98 (0.89 to 1.07) | 0.752 |
Current smoker, cigarettes ≥20/day | 1.05 (0.96 to 1.16) | 0.237 |
Alcohol consumption | ||
Never | Ref. | |
Not more than once per month | 0.89 (0.78 to 1.03) | 0.125 |
1–3 times per month | 1.17 (1.04 to 1.32) | 0.006 |
1–2 times per week | 1.00 (0.89 to 1.12) | 0.963 |
3–4 times per week | 1.05 (0.92 to 1.21) | 0.412 |
On a daily basis | 1.18 (1.06 to 1.31) | 0.002 |
Physical activity | ||
Very light | Ref. | |
Light | 0.92 (0.83 to 1.02) | 0.154 |
Moderate | 0.99 (0.88 to 1.11) | 0.930 |
Heavy and very heavy | 0.91 (0.82 to 1.02) | 0.118 |
*Estimated time effect of age, p<0.001.