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. 2021 Jan 18;41(4):738–747. doi: 10.1007/s10875-020-00949-6

Table 2.

Number of COVID-19 patients with individual cytokine elevation

All Moderate (N = 114) Severe (N = 54) Critical (N = 71)
Toci No Toci Toci No Toci Toci No Toci
Cytokine (N = 239) (N = 39) (N = 75) (N = 48) (N = 6) (N = 66) (N = 5)
IL-6, No. (%) 184 (77.0) 34 (87.2) 40 (53.3) 41 (85.4) 4 (66.7) 61 (92.4) 4 (80.0)
sIL2R, No. (%) 121 (50.6) 17 (43.6) 26 (34.6) 26 (54.2) 3 (50.0) 48 (72.7) 1 (20.0)
IL-10, No. (%) 54 (22.6) 4 (10.3) 9 (12.0) 13 (27.1) 0 (0.0) 25 (37.9) 3 (60.0)
IFN-Y, No. (%) 70 (29.3) 11 (28.2) 14 (18.7) 18 (37.5) 0 (0.0) 27 (40.9) 0 (0.0)
IL-1 B, No. (%) 41 (17.2) 5 (12.8) 13 (17.3) 9 (18.8) 0 (0.0) 13 (19.7) 1 (20.0)
IL-12, No. (%) 23 (9.6) 3 (7.7) 7 (9.3) 7 (14.6) 0 (0.0) 6 (9.1) 0 (0.0)
IL-13, No. (%) 10 (4.2) 1 (2.6) 2 (2.7) 2 (4.1) 0 (0.0) 5 (7.6) 0 (0.0)
IL-17, No (%) 34 (14.2) 3 (7.7) 14 (18.7) 5 (10.4) 0 (0.0) 10 (15.2) 2 (40.0)
IL-2, No (%) 60 (25.1) 11 (28.2) 15 (20.0) 14 (29.2) 0 (0.0) 19 (28.8) 1 (20.0)
IL-4, No. (%) 12 (5.0) 1 (2.5) 3 (4.0) 4 (8.3) 0 (0.0) 4 (6.1) 0 (0.0)
IL-5, No. (%) 11 (4.6) 1 (2.5) 2 (2.7) 2 (4.2) 0 (0.0) 6 (9.1) 0 (0.0)
IL-8, No. (%) 17 (7.1) 3 (7.7) 1 (1.3) 2 (4.2) 0 (0.0) 11 (16.7) 0 (0.0)
TNF-a, No. (%) 35 (14.6) 2 (5.1) 11 (14.7) 10 (20.8) 0 (0.0) 11 (16.7) 1 (20.0)