Table 1.

Characteristics of different pain types.

Pain	Pain is defined as an “unpleasant sensory experience associated with actual or potential tissue damage or described in terms of such damage” (5).
Nociceptive pain	Nociceptive pain occurs as an appropriate encoding of noxious or potentially noxious stimuli. It represents a physiological response that the patient becomes conscious of when nociceptors in bone, muscle, or any body tissue are activated, warning the organism of tissue damage. In response, coordinated reflexes and behavioral responses are elicited (5, 6).
Neuropathic pain	Pain caused by a lesion in, or disease of, the somatosensory nervous system (7).
Acute pain	Physiological response to an acute disease-related damage (8, 9), here NMOSD- or MOGAD-attack related.
Chronic pain	Pain that persists or recurs for more than 3 months (9), (https://www.iasp-pain.org/).