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. 2020 Dec;8(24):1649. doi: 10.21037/atm-20-7165

Table 1. Genes which are reported related with congenital hypothyroidism.

Genes Location Exons Full name
SLC26A4 (PDS) 7q31 23 Solute carrier family 26 (anion exchanger), member 4
   TSHR 14q31 12 Thyroid stimulating hormone receptor
   TPO 2p25 19 Thyroid peroxidase
MCT8(SLC16A2) Xq13 6 Solute carrier family 16 (monocarboxylic acid transporters), member 2
   TG 8q24 52 Thyroglobulin
   PAX8 2q13 12 Paired box (PAX) family of transcription factors
   TSHB 1p13 3 Thyroid stimulating hormone, beta
   THRB 3p24.2 17 Thyroid hormone receptor, beta
   DUOX2 15q15.3 34 Dual oxidase 2
SLC5A5 (NIS) 19p13.11 16 Solute carrier family 5 (sodium/iodide cotransporter), member 5
   NKX2-1 14q13 3 NK2 homeobox 1
   FOXE1 9q22 1 Forkhead box E1
   PDE8B 5q13.3 26 Phosphodiesterase 8B
   GNAS 20q13.3 16 GNAS complex locus
   TTF2 1p22 25 Transcription termination factor, RNA polymerase
   POU1F1 3p11 6 POU class 1 homeobox 1
   GLIS3 9p24.2 19 GLIS family zinc finger 3
DEHAL1 (IYD) 6q25.1 7 Iodotyrosine deiodinase
   THRA 17q11.2 11 Thyroid hormone receptor, alpha
   IGSF1 Xq25 23 Immunoglobulin superfamily, member 1
   DUOXA2 15q15.1 6 Dual oxidase maturation factor 2