Table 1. Clinical and laboratory characteristics of MPE patients.
| Characteristic | TNFR2+Treg high (n=15) | TNFR2+Treg low (n=26) | P value |
|---|---|---|---|
| Age, median [range], yrs | 65 [52–72] | 68 [61.5–70.5] | 0.9321 |
| Male, No., % | 9/15 [60] | 18/26 [69.2] | 0.5483 |
| Smoking history, No., % | |||
| Current smoker | 4/15 [26.7] | 7/26 [26.9] | 0.9858 |
| Ex-smoker | 4/15 [26.7] | 6/26 [23.1] | 0.7966 |
| Never-smoker | 7/15 [46.7] | 13/26 [50] | 0.8370 |
| Body mass index, median [range] | 20.93 [19.16–22.34] | 22.79 [21.12–24.13] | 0.0831 |
| EGFR mutations | |||
| Positive, No., % | 5/8 [62.5] | 8/10 [80] | 0.4101 |
| Pleural effusion | |||
| Total cell count (106/L) | 10,399 [1,921–65,802] | 12,500 [2,025–63,429] | 0.7342 |
| Total WBC (106/L) | 704 [307–1,226] | 1,289 [403–1,900] | 0.1802 |
| Mononuclear WBC (%) | 78 [64–88] | 76 [56–94] | 0.7844 |
| Multinuclear WBC (%) | 22 [12–36] | 24 [7–44] | 0.8008 |
| Neutrophil-lymphocyte ratio | 0.28 [0.14–0.56] | 0.32 [0.07–0.79] | 0.7094 |
| Carcinoembryonic antigen (mg/L) | 424.2 [41.4–1266] | 566.5 [77.78–1,500] | 0.8414 |
| Lactose dehydrogenase (U/L) | 350 [245–761] | 540 [252–650.5] | 0.3443 |
| Adenosine deaminase (U/L) | 8 [6–11.75] | 8 [6.5–13.5] | 0.8215 |
| Total protein (g/L) | 40.2 [35.4–42.65] | 44.9 [35–49.2] | 0.1197 |
| Albumin (g/L) | 26.9 [22.4–30.7] | 28 [24–33.7] | 0.4080 |
| Cholesterol (mmol/L) | 2.16 [1.62–2.62] | 2.1 [1.89–2.62] | 0.9285 |
Data are presented as medians [interquartile ranges, IQR] and n/N (%). MPE, malignant pleural effusion; EGFR, epidermal growth factor receptor; WBC, white blood cell count.