Table 2. Univariate analysis for DFS and OS of LUAD based on TCGA dataset.
| Variables | DFS | OS | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| QTRT1 (high vs. low) | 1.32 | 1.03–1.68 | 0.026 | 1.26 | 1.02–1.56 | 0.031 | |
| Age (≥60 vs. <60) | 1.06 | 0.82–1.37 | 0.661 | 0.97 | 0.77–1.23 | 0.808 | |
| Gender | 0.96 | 0.75–1.22 | 0.730 | 0.93 | 0.75–1.14 | 0.475 | |
| ALK | 0.99 | 0.78–1.26 | 0.924 | 0.95 | 0.77–1.18 | 0.648 | |
| EGFR | 1.32 | 1.04–1.68 | 0.024 | 1.21 | 0.98–1.49 | 0.078 | |
| KRAS | 1.30 | 1.02–1.66 | 0.034 | 1.32 | 1.07–1.64 | 0.010 | |
| LHX5 | 0.84 | 0.66–1.07 | 0.154 | 0.86 | 0.70–1.07 | 0.172 | |
| NRAS | 0.88 | 0.69–1.13 | 0.315 | 0.90 | 0.73–1.12 | 0.345 | |
| PIK3CA | 0.99 | 0.78–1.27 | 0.944 | 0.97 | 0.79–1.20 | 0.804 | |
| TP53 | 1.11 | 0.88–1.42 | 0.380 | 1.15 | 0.93–1.42 | 0.194 | |
DFS, disease-free survival; OS, overall survival; LUAD, lung adenocarcinoma; TCGA, The Cancer Genome Atlas; QTRT1, queuine tRNA-ribosyltransferase 1; HR, hazard ratio; CI, confidence interval; ALK, anaplastic lymphoma kinase; EGFR, epidermal growth factor receptor; KRAS, kirsten rat sarcoma viral oncogene; LHX5, LIM homeobox 5; NRAS, neuroblastoma RAS viral (v-ras) oncogene homolog; PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; TP53, tumor protein p53.