Table 2. Outcomes.
| Outcomes | APRV (n=206) | LTV (n=199) | Analysis method | 95% CI | P value |
|---|---|---|---|---|---|
| Hospital mortality | 206 | 199 | M-H, fixed, odds ratio | 0.57 (0.37, 0.88) | 0.01 |
| Ventilator-free days at day 28 (days) | 190 | 183 | IV, random, mean difference | 5.36 (1.99, 8.73) | 0.002 |
| Respiratory system compliance at day 3 (mL/cmH2O) | 104 | 98 | IV, random, mean difference | 8.19 (0.84, 15.54) | 0.03 |
| Length of ICU stay (days) | 160 | 155 | IV, random, mean difference | −0.45 (−6.56, −2.44) | <0.0001 |
| PaO2/FiO2 at day 3 | 151 | 143 | IV, random, mean difference | 44.40 (16.05, 72.76) | 0.002 |
| MAP at day 3 (mmHg) | 146 | 139 | IV, random, mean difference | 4.18 (3.10, 5.25) | <0.00001 |
| Pneumothorax | 87 | 83 | M-H, fixed, odds ratio | 0.40 (0.12, 1.34) | 0.14 |
APRV, airway pressure release ventilation; LTVV, low tidal volume ventilation; CI, confidence interval; ICU, intensive care unit; MAP mean arterial pressure.