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. 2020 Dec;8(24):1651. doi: 10.21037/atm-20-7703

Figure 5.

Figure 5

FOXP3 exerted a protective effect by mediating the miR-146b-5p/Robo1/NF-κB system in the ALI model. (A) The protein relative levels of p-65 and Robo1 were detected by western blot in the control group, ALI model group, ALI model group of infection Ad-FOXP3, ALI model group of infection Ad-Robo1, and ALI model group of both infection Ad-FOXP3and Ad-Robo1. (B) HE staining detected lung pathological damage. Magnification 200×. The expression levels of inflammation factors TNF-α (C), IL-6 (D) and IL-1β (E) in lung tissue were detected by ELISA. *, P<0.05, **, P<0.01, compared with control group; #, P<0.05, ##, P<0.01, compared with ALI model group; &, P<0.05, compared with ALI model group of infection Ad-Robo1.