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Treatment of db/db mice with SAL decreased NOX4 expression and NADPH oxidase activity. A(i), representative immunoblots of NOX4 expression of glomeruli. A(ii), quantitative results of immunoblots from A(i). B(i), glomeruli mRNA levels of NOX4 from different intervened groups were assessed by real‐time PCR. B(ii), histogram representing NADPH oxidase activity in glomeruli lysates from different intervened groups. ** P < .01, *** P < .001 vs vehicle‐treated db/db mice (n = 6)
