TABLE 1.
Parameter | db/m + vehicle | db/m + SAL | db/db + vehicle | db/db + SAL |
---|---|---|---|---|
Fasting blood glucose (mM) | 8.15 ± 1.00 | 7.90 ± 3.20 | 28.20 ± 3.00 a | 20.50 ± 2.80 a |
Body weight (BW, g) | 26.74 ± 1.20 | 27.32 ± 2.01 | 54.21 ± 3.24 a | 52.90 ± 2.83 a |
KW/BW (mg/g) | 11.42 ± 1.98 | 10.32 ± 1.54 | 9.4 ± 1.03 a | 9.8 ± 1.56 a |
Serum creatinine (mg/dL) | 42.25 ± 1.93 | 51.50 ± 1.32 | 58.25 ± 1.93 a | 54.50 ± 1.71 a |
Urine albumin to creatinine (mg/g) | 32.2 ± 1.2 | 30.8 ± 1.4 | 212.3 ± 4.5 a | 54.9 ± 1.9 a , b |
Dara are expressed as the mean ± SEM.
P < .05 compared with db/m + vehicle group.
P < .05 compared with db/db + vehicle group.