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. 2021 Jan 18;20(3):217–243. doi: 10.1038/s41573-020-00093-1

Fig. 7. Timeline of key developments in translational glycobiology.

Fig. 7

Important events that have catalysed biological discovery and drug development are highlighted for each thread of this Review. Tn denotes a single O-GalNAc. ADC, antibody–drug conjugate; CAR, chimeric antigen receptor; GalNAc, N-acetylgalactosamine; GWAS, genome-wide association studies; HCELL, haematopoietic cell E-/L-selectin ligand; HSC, haematopoietic stem cell; KLH, keyhole limpet haemocyanin; Ley, Lewisy; MUC1, mucin 1; PSGL1, P-selectin glycoprotein ligand 1; rPSGL–Ig, recombinant PSGL1 fused to immunoglobulin; SHP, SRC homology region 2 domain-containing phosphatase; SNP, single-nucleotide polymorphism; sLea, sialyl Lewisa; sLex, sialyl Lewisx; sTn, sialyl-Tn; TIL, tumour-infiltrating lymphocyte.