Table 2.
Characteristics of 616 Study Participants by Tertile of Mitochondrial Oxidative Capacity (τ PCr, s)
| Tertile 1 | Tertile 2 | Tertile 3 | ||
|---|---|---|---|---|
| τ PCr < 43.7 | 43.8–55 | 55–87.7 | ||
| Characteristci | (n = 206) | (n = 205) | (n = 205) | p Valuea |
| Age, y | 59 (15.7) | 66.5 (14.6) | 72.9 (11.9) | <.0001 |
| Female sex, % | 52.4 | 52.7 | 59.0 | .31 |
| Smoking, current, % | 1.0 | 2.0 | 2.0 | .66 |
| Body mass index, kg/m2 | 26.0 (4.1) | 27.0 (4.6) | 27.1 (4.7) | .01 |
| Lean body mass, kg | 16.7 (3.7) | 15.9 (3.8) | 15.3 (3.4) | .0001 |
| Fat body mass, kg | 9.2 (4.4) | 9.7 (3.7) | 10.1 (4.2) | .013 |
| Physical activity, min/wk | 168 (205) | 84.5 (137) | 75.2 (141.8) | <.0001 |
| Systolic blood pressure, mm Hg | 113.2 (13.2) | 115.4 (14.3) | 114.4 (13.5) | .37 |
| Total cholesterol, mmol/L | 4.8 (0.9) | 4.8 (1.0) | 4.7 (1.0) | .14 |
| HDL cholesterol, mmol/L | 1.7 (0.4) | 1.6 (0.5) | 1.7 (0.5) | .99 |
| Diabetes mellitus, % | 7.3 | 15.1 | 19.5 | .0001 |
| Hypertension, % | 22.3 | 31.7 | 46.8 | <.0001 |
| Framingham Risk Score | 8 (5.5) | 10.8 (5.8) | 11.9 (4.5) | <.0001 |
| CVD events, N | 0.1 (0.3) | 0.1 (0.5) | 0.2 (0.6) | .007 |
| CVD positive history, % | ||||
| Any | 6.8 | 9.3 | 14.1 | .01 |
| Angina or MI | 2.4 | 2.9 | 5.9 | .06 |
| TIA or stroke | 3.4 | 3.4 | 5.9 | .22 |
| PAD | 0.5 | 0.5 | 1 | .06 |
Notes: CV = cardiovascular; MI = myocardial infarction; PAD = peripheral artery disease; TIA = transient ischemic attack. Mean (SD) or % values.
aANOVA for continuous variables; Pearson chi-squared test for categorical variables.