Table 5. IV and PO PK Profiles of Compounds 14, 23, and 32.

	14	23	32
Rat IV PK (1mg/kg)
C1 (mL/min/kg)/Clu	40/3571	12/170	34/3400
T1/2 (h)	1	2.6	1
Vss(L/kg)	3	2.3	1.7
Rat PO PK (5mg/kg)
AUCo-inf (μg·h/mL)	7.1		6.8
Cmax (μg/mL)	2.1		1.1
T1/2 (h)	1.3		2.7
% F	100		100