Fig. 3.

Active and differentially active HARs and HGEs identified by MPRA. (A and B) The proportion of inactive, active, and differentially active HGEs (A) and HARs (B). (C and D) The distribution of the number of differentially active fragments per HGE (C) and HAR (D). Most species-biased HGEs and HARs contain only one differentially active MPRA fragment. There are an additional 18 HGEs that contain both human- and chimpanzee-biased fragments in different parts of their sequence (not included in C).