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. 2021 Feb;27(2):202–220. doi: 10.1261/rna.078097.120

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© 2021 Seelam Prabhakar et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 10. — (A) Stacking interactions between base 37 and neighboring nucleobases in the anticodon loop of yeast tRNA and (B) hydrogen-bonding interactions (with occupancies) between bases 37 and 33 throughout the MD simulations for unmodified, m¹G and yW-modified yeast tRNAs. (C) consensus secondary structures of the anticodon stem–loop region in unmodified and modified tRNA, with the solid red circle representing the nucleotide at the 37th position of yeast tRNA. The color scheme shows the probability distribution of the interactions within the cluster.