Table 3. Functional roles of four hub genes.

No.	Gene symbol	Full name	Function
1	MAPK-14	Mitogen-activated protein kinase 14	Play an important role in the cascades of cellular responses evoked and inhibit the lysosomal degradation pathway of autophagy
2	PTPRC	Protein tyrosine phosphatase receptor type C	High expression of PTPRC is associated with progression of PTP family
3	PTPN12	Protein tyrosine phosphatase non-receptor type 12	High expression of PTPN12 is associated with progression of PTP family
4	B9D1	B9 domain containing 1	Component of the tectonic-like complex and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes