Table 1.
Baseline Characteristics of 867 Glioblastoma Patients Included in the Final Analysis
| Parameter | N (%) or Mean (±SD) |
|---|---|
| Age, years | 63.83 (±11.51) |
| Sex, male | 501 (57.8%) |
| Medical history | |
| Arterial hypertension | 450 (51.9%) |
| Diabetes mellitus | 150 (17.3%) |
| Hypothyroidism | 104 (12.0%) |
| History of cancer | 127 (14.6%) |
| KPS at admissiona | |
| Good (90–100%) | 338 (39.7%) |
| Reduced (70–80%) | 414 (48.6%) |
| Poor (≤60%) | 100 (11.7%) |
| EOR, biopsy | 247 (28.5%) |
| Tumor location | |
| Frontal lobe | 305 (35.2%) |
| Temporal lobe | 239 (27.6%) |
| Parietal lobe | 103 (11.9%) |
| Occipital lobe | 129 (14.9%) |
| Midline/Infratentorial/Bi-hemispheric | 91 (10.5%) |
| Molecular status | |
| MGMT methylation | 310 (41.6%b) |
| IDH1 mutation | 17 (3.1%c) |
EOR, extent of resection; IDH1-Isocitrate dehydrogenase 1 mutation; MGMT, O[6]-methylguanine-DNA methyltransferase promoter methylation; N, number of cases; SD, standard deviation.
a15 cases (1.7%) with missing KPS score.
b121 cases (14%) with missing MGMT promoter methylation status.
c311 cases (35.9%) with missing IDH1 mutation status.