Table 2.
Shortened List of Univariate Assessments Between the Patients’ Characteristics and the Occurrence of SAO and EPS (for the full list with over 100 tested variables—see the Supplementary Table S1)
| Parameter | SAO | EPS | ||
|---|---|---|---|---|
| OR (95% CI)/mean (±SD) | P-value | OR (95% CI)/mean (±SD) | P-value | |
| Age | 61.24 (±12.16) vs 64.21 (±12.42) | .001 | 63.62 (±13.49) vs 63.39 (±12.32) | .677 |
| Arterial hypertension | 0.94 (0.69–1.27) | .695 | 1.74 (1.02–2.96) | .040 |
| History of cancer | 0.72 (0.46–1.14) | .193 | 1.87 (1.03–3.40) | .049 |
| Location: parietal lobe | 1.96 (1.28–3.01) | .003 | 0.57 (0.22–1.44) | .327 |
| Location: frontal/temporal lobe | 1.28 (0.93–1.76) | .149 | 2.07 (1.15–3.75) | .017 |
| EOR: Surgery vs Biopsy | 1.87 (1.30–2.68) | .001 | 1.72 (0.92–3.21) | .092 |
| EOR: GTR vs Debulking | 1.64 (1.15–2.35) | .006 | 0.42 (0.23–0.76) | .005 |
| GFAP staining. ≥ 35% | 1.88 (1.02–3.47) | .053 | 0.91 (0.37–2.28) | .812 |
| KPS % continuous | 83.16 (±12.19) vs 78.67 (±13.18) | <.0001 | 78.09 (±13.74) vs 80.09 (±12.99) | .304 |
| Erythrocyte < 4.0/pL | 2.12 (0.99–4.55) | .079 | 4.28 (1.74–10.48) | .004 |
| WBC > 11/nL | 0.40 (0.28–0.55) | <.0001 | 1.09 (0.66–1.82) | .796 |
| Hemoglobin < 12 g/dL | 1.43 (0.75–2.72) | .285 | 3.34 (1.53–7.29) | .005 |
| Hematocrit < 35% | 1.44 (0.70–2.94) | .332 | 3.16 (1.33–7.55) | .015 |
| PLT > 400/nL | 0.32 (0.11–0.90) | .022 | 0.32 (0.04–2.34) | .352 |
| Sodium < 140 mmol/L | 0.67 (0.49–0.94) | .019 | 1.17 (0.70–1.97) | .591 |
| Chloride > 102 mmol/L | 1.72 (1.22–2.42) | .002 | 0.84 (0.50–1.43) | .581 |
| Calcium > 2.35 mmol/L | 1.75 (1.24–2.46) | .002 | 0.49 (0.26–0.95) | .039 |
| Urea > 20 mg/dL | 0.53 (0.39–0.73) | <.0001 | 1.62 (0.97–2.71) | .068 |
| GGT > 55 U/L | 0.99 (0.67–1.47) | 1.000 | 2.19 (1.26–3.81) | .008 |
| Total protein <7.0 g/dL | 0.67 (0.48–0.92) | .014 | 1.83 (1.05–3.18) | .033 |
| CRP >=1.0 mg/dL | 0.96 (0.58–1.59) | .898 | 3.00 (1.39–6.51) | .006 |
| PLT/WBC > 25 | 1.64 (1.20–2.24) | .002 | 0.82 (0.50–1.38) | .519 |
| WBC/MPV < 0.9 | 2.69 (1.87–3.88) | <.0001 | 1.12 (0.63–2.00) | .768 |
CRP, C-reactive protein; EOR, extent of resection; GFAP, glial fibrillary acidic protein immunohistochemistry staining percentage; GGT, gamma-glutamyl-transferase; GTR, gross total resection; MPV, mean platelet volume; OR, odds ratio; PLT, blood platelets; SD, standard deviation; WBC, white blood cells. Differences with a P ≤ .05 were regarded as statistically significant.