Table 1.
Variable | Total n = 1690 | ||
---|---|---|---|
Demographics | |||
Age (years; median IQR) | 70 (55–80) | ||
Sex | |||
Male | 976 (57.8) | ||
Female | 714 (42.2) | ||
Charlson Comorbidity Index | 1 (0–3) | ||
Cardiac comorbidities | 301 (17.8) | ||
Hypertension | 373 (22.1) | ||
Chronic pulmonary disease | 263 (15.6) | ||
Cerebrovascular diseasea | 139 (8.2) | ||
Renal insufficiency | 255 (15.1) | ||
Liver disease | 53 (3.1) | ||
Diabetes | 255 (15.1) | ||
Solid malignancies | 176 (10.4) | ||
Solid metastatic malignancies | 177 (10.5) | ||
Hematological malignancies | 53 (3.2) | ||
SOFA score at admission (median IQR) | 2 (0–3) | ||
Central lineb at admission | 193 (11.4) | ||
Oxygen Therapy | |||
Noninvasive | 307 (18.2) | ||
Invasive | 11 (0.7) | ||
Vasopressor use | 17 (1.0) | ||
Outcomes | |||
In-hospital mortality | 90 (5.3) | ||
ICU admission | 131 (7.8) | ||
Bacteremia | 253 (15.0) | ||
LOS (days; median IQR) | 5 (3–10) | ||
ICU LOS (days; median IQR) | 3 (2–8) | ||
Clinical Infection Diagnosis | Bacteremia (n = 253) | No Bacteremia (n = 1437) | |
Pneumonia | 291 (17.2) | 24 (9.5) | 267 (18.6) |
ABSSSI | 164 (9.7) | 14 (5.5) | 150 (10.4) |
Intra-abdominal infection | 158 (9.3) | 43 (17.0) | 115 (8.0) |
Urosepsis | 97 (5.7) | 97 (38.3) | 0 (0.0) |
Influenza | 97 (5.7) | 0 (0.0) | 97 (6.8) |
lRTI | 93 (5.5) | 0 (0.0) | 93 (6.5) |
BSI, CLABSI, and endocarditis | 73 (4.3) | 73 (28.9) | 0 (0.0) |
uUTI | 60 (3.6) | 0 (0.0) | 60 (4.2) |
Other Infection | |||
Fever | 127 (7.5) | 0 (0.0) | 127 (8.8) |
lUTI | 90 (5.3) | 0 (0.0) | 90 (6.3) |
uRTI | 66 (3.9) | 0 (0.0) | 66 (4.6) |
Neutropenic fever | 33 (2.0) | 0 (0.0) | 32 (2.3) |
Bone and joint infection | 13 (0.8) | 1 (0.4) | 12 (0.8) |
Viral infectionc | 12 (0.7) | 0 (0.0) | 12 (0.8) |
CNS infection | 9 (0.5) | 1 (0.4) | 8 (0.6) |
Other | 9 (0.5) | 0 (0.0) | 9 (0.6) |
Other bacterial/parasitic infection | 4 (0.2) | 0 (0.0) | 4 (0.3) |
No Infection Diagnosis | |||
Suspected infection | 230 (13.6) | 0 (0.0) | 230 (16.0) |
Suspected viral infection | 44 (2.6) | 0 (0.0) | 44 (3.1) |
Inflammatory diseases | 20 (1.2) | 0 (0.0) | 20 (1.4) |
Abbreviations: ABSSSI, acute bacterial skin and skin structure infection; BSI, bloodstream infection; CLABSI, central line-associated BSI; CNS, central nervous system; ICU, intensive care unit; IQR, interquartile range; lRTI, lower respiratory tract infection; lUTI, lower urinary tract infection; LOS, length of stay; SOFA, sequential organ failure assessment; uRTI, upper respiratory tract infection; uUTI, upper urinary tract infection.
NOTE: Numbers are presented as N (%) unless specified.
aCerebrovascular disease included strokes and transient ischemic attack.
bThese were 188 portal catheters and 5 Hickman catheters.
cViral infections were herpes zoster (n = 3), cytomegalovirus (n = 2), Epstein-Barr virus, herpes simplex, enterovirus, measles, rhinovirus, parainfluenza virus, and human immunodeficiency virus (all n = 1).