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. 2020 Dec 28;8(1):ofaa594. doi: 10.1093/ofid/ofaa594

Table 1.

Patient Characteristics, Disease Severity, Clinical Outcomes, Final Infection Diagnoses, and Proportion of Patients With Bacteremia

Variable Total n = 1690
Demographics
Age (years; median IQR) 70 (55–80)
Sex
 Male 976 (57.8)
 Female 714 (42.2)
Charlson Comorbidity Index 1 (0–3)
 Cardiac comorbidities 301 (17.8)
 Hypertension 373 (22.1)
 Chronic pulmonary disease 263 (15.6)
 Cerebrovascular diseasea 139 (8.2)
 Renal insufficiency 255 (15.1)
 Liver disease 53 (3.1)
 Diabetes 255 (15.1)
 Solid malignancies 176 (10.4)
 Solid metastatic malignancies 177 (10.5)
 Hematological malignancies 53 (3.2)
SOFA score at admission (median IQR) 2 (0–3)
Central lineb at admission 193 (11.4)
Oxygen Therapy
 Noninvasive 307 (18.2)
 Invasive 11 (0.7)
Vasopressor use 17 (1.0)
Outcomes
In-hospital mortality 90 (5.3)
ICU admission 131 (7.8)
Bacteremia 253 (15.0)
LOS (days; median IQR) 5 (3–10)
ICU LOS (days; median IQR) 3 (2–8)
Clinical Infection Diagnosis Bacteremia (n = 253) No Bacteremia (n = 1437)
Pneumonia 291 (17.2) 24 (9.5) 267 (18.6)
ABSSSI 164 (9.7) 14 (5.5) 150 (10.4)
Intra-abdominal infection 158 (9.3) 43 (17.0) 115 (8.0)
Urosepsis 97 (5.7) 97 (38.3) 0 (0.0)
Influenza 97 (5.7) 0 (0.0) 97 (6.8)
lRTI 93 (5.5) 0 (0.0) 93 (6.5)
BSI, CLABSI, and endocarditis 73 (4.3) 73 (28.9) 0 (0.0)
uUTI 60 (3.6) 0 (0.0) 60 (4.2)
Other Infection
Fever 127 (7.5) 0 (0.0) 127 (8.8)
lUTI 90 (5.3) 0 (0.0) 90 (6.3)
uRTI 66 (3.9) 0 (0.0) 66 (4.6)
Neutropenic fever 33 (2.0) 0 (0.0) 32 (2.3)
Bone and joint infection 13 (0.8) 1 (0.4) 12 (0.8)
Viral infectionc 12 (0.7) 0 (0.0) 12 (0.8)
CNS infection 9 (0.5) 1 (0.4) 8 (0.6)
Other 9 (0.5) 0 (0.0) 9 (0.6)
Other bacterial/parasitic infection 4 (0.2) 0 (0.0) 4 (0.3)
No Infection Diagnosis
Suspected infection 230 (13.6) 0 (0.0) 230 (16.0)
Suspected viral infection 44 (2.6) 0 (0.0) 44 (3.1)
Inflammatory diseases 20 (1.2) 0 (0.0) 20 (1.4)

Abbreviations: ABSSSI, acute bacterial skin and skin structure infection; BSI, bloodstream infection; CLABSI, central line-associated BSI; CNS, central nervous system; ICU, intensive care unit; IQR, interquartile range; lRTI, lower respiratory tract infection; lUTI, lower urinary tract infection; LOS, length of stay; SOFA, sequential organ failure assessment; uRTI, upper respiratory tract infection; uUTI, upper urinary tract infection.

NOTE: Numbers are presented as N (%) unless specified.

aCerebrovascular disease included strokes and transient ischemic attack.

bThese were 188 portal catheters and 5 Hickman catheters.

cViral infections were herpes zoster (n = 3), cytomegalovirus (n = 2), Epstein-Barr virus, herpes simplex, enterovirus, measles, rhinovirus, parainfluenza virus, and human immunodeficiency virus (all n = 1).