Table 1.
Recode for Brain and Other Central Nervous System Tumors (SEER Brain and CNS Recode) Diagnosed in the SEER 21 Registries, 2004–2017
| Category | ICD-O-3 Site | Malignant | Nonmalignant | ||||
|---|---|---|---|---|---|---|---|
| ICD-O-3 Morphology | Cases | ASR | ICD-O-3 Morphology | Cases | ASR | ||
| Brain and Other Nervous System (SEER Site Recode) | C700-C729 | All except 9050–9055, 9140, 9590–9992 | 107,890 | 6.5 | All except 9050–9055, 9140, 9590–9992 | 207,294 | 9.9 |
| Glioma | C700-C729 | 9380–9384, 9391–9460 | 95,198 | 5.7 | – | – | – |
| Diffuse astrocytoma and anaplastic astrocytoma | C700-C729 | 9400/3, 9401/3, 9410/3, 9411/3, 9420/3b | 14,363 | 0.9 | – | – | – |
| Glioblastoma | C700-C729 | 9440/3, 9441/3, 9442/3, 9445/3a | 54,832 | 3.2 | – | – | – |
| Diffuse midline glioma, H3 K27M-mutant | C700-C729 | 9385/3a | – | – | – | – | – |
| Oligodendroglioma | C700-C729 | 9450/3, 9451/3 | 6,031 | 0.4 | – | – | – |
| Oligoastrocytoma | C700-C729 | 9382/3 | 2,694 | 0.2 | – | – | – |
| Other astrocytic tumors | C700-C729 | 9421/3c, 9424/3, 9425/3a | 5,668 | 0.4 | 9384/1 | 423 | 0.0 |
| Gliomas, unspecified | C700-C729 | 9380/3 | 7,472 | 0.5 | – | – | – |
| Other gliomas | C700-C729 | 9430/3 | 62 | 0.0 | 9431/1,a 9444/1 | 42 | 0.0 |
| Ependymal tumors | C700-C729 | 9391/3, 9392/3, 9393/3, 9396/3a | 4,076 | 0.3 | 9383/1, 9394/1 | 2,652 | 0.1 |
| Embryonal tumors | C700-C729 | 8963/3, 9364/3e, 9470/3, 9471/3, 9472/3, 9473/3, 9474/3, 9475/3a, 9476/3a, 9477/3a, 9478/3a, 9490/3, 9500/3, 9501/3, 9502/3, 9508/3 | 3,581 | 0.2 | – | – | – |
| Meningioma | C700-C729 | 9530/3, 9538/3, 9539/3 | 1,675 | 0.1 | 9530/0, 9531/0, 9532/0, 9533/0, 9534/0, 9537/0, 9538/1, 9539/1 | 146,498 | 7.0 |
| Tumors of the cranial and paraspinal nerves | C700-C729 | – | – | – | 9540/0, 9550/0, 9560/0, 9560/1, 9571/0 | 33,823 | 1.6 |
| Choroid plexus tumors | C700-C729 | 9390/3 | 151 | 0.0 | 9390/0, 9390/1 | 750 | 0.0 |
| Neuronal and mixed neuronal-glial tumors | C700-C729 | 9505/3 | 191 | 0.0 | 8693/1, 9412/1, 9413/0, 9492/0, 9493/0, 9505/1, 9506/1, 9509/1d | 3,602 | 0.2 |
| Tumors of the pineal region | C753 | 9362/3, 9395/3d | 427 | 0.0 | 9361/1 | 250 | 0.0 |
| Mesenchymal, nonmeningothelial tumors | C700-C729 | – | – | – | 8815/0,f 8815/1,f 8821/1, 8825/0, 8825/1, 8830/0, 8850/0, 8861/0, 8880/0,d 8890/0, 8900/0, 9120/0, 9161/1, 9180/0, 9210/0, 9220/0 | 5,024 | 0.2 |
ICD-O-3, International Classification of Diseases for Oncology, 3rd edition; ASR, Age-standardized rate per 100,000.
aNew code in the 2016 CNS WHO and SEER. Effective with cases diagnosed 1/1/2018 and forward.
bCode 9420/3 has been deleted from the 2016 CNS WHO since this diagnosis overlaps nearly entirely with the standard diffuse astrocytoma. For that reason, it has been added to category “Diffuse astrocytoma and anaplastic astrocytoma.”
cThe behavior for code 9421/3 is /1 in the 2016 CNS WHO but /3 in SEER and CBTRUS.
dNew code in SEER. Effective with cases diagnosed 1/1/2018 and forward.
eUnder “Mesenchymal, nonmeningothelial tumors” in the 2016 CNS WHO.
fNew term. Effective with cases diagnosed 1/1/2018 and forward.