Table 5.
Means (SD) of baseline SF-361 quality of life scores in SCD patients without and with macro and micro nutritional deficiencies versus control subjects.
| Scores (norm) | SCD patients with no macro or micro-nutrient deficiencies (n=20) | SCD patients with macro or micro-nutrient deficiencies (n=42) | P-value | Control subjects (n=50) | P value between SCD patients and controls |
|---|---|---|---|---|---|
| PF | 84.05 ± 2.81 | 80.50 ± 3.19 | <0.0001 | 90.10 ± 2.40 | <0.0001** |
| RP | 88.21± 1.71 | 86.83 ± 1.34 | 0.0013 | 90.48 ± 3.4 | 0.0008 |
| BP | 82.13 ± 2.42 | 80.21 ±2.25 | <0.0001 | 84.63± 3.36 | 0.0002 |
| GH | 52.89 ± 2.37 | 50.25± 1.75 | <0.0001 | 54.24± 3.11 | 0.0377* |
| VT | 55.34 ± 2.33 | 53.21 ± 1.56 | <0.0001 | 59.35 ± 3.617 | 0.0001** |
| SF | 88.29 ± 2.18 | 86.83 ± 1.52 | <0.0001 | 91.47 ± 3.9 | <0.0001** |
| RE | 83.97 ± 3.31 | 81.83 ± 3.76 | 0.006 | 88.53 ± 8.56 | <0.0001** |
| MH | 72.09 ± 3.18 | 71.79 ± 2.67 | 0.058 | 72.10 ± 4.3 | 0.3112 |
| PCS | 43.74 ± 1.54 | 41.04± 1.73 | <0.0001 | 47.81 ± 2.7 | <0.0001** |
| MCS | 49.21 ± 1.72 | 49.01 ± 1.82 | 0.062 | 50.07 ± 1.11 | 0.0255 |
SF-36, short-form quality of life score with 36 questions. HRQoL: health- related quality of life. AC, activity; BP, bodily pain; EF, emotional function; FA, fatigue; GH, general health; MCS, Mental Component Summary Score; MH, mental health; PCS, Physical Component Summary Score; PF, physical functioning; RE, Role Emotional; RP, role physical; SF, social functioning; SS, systemic symptoms; VT, vitality; WO, worry.
Significant difference between the study groups (P<0.05).
Highly significant difference between the two study groups (P<0.01, 0.001).
Significant differences existed between patients with SCD and control subjects as well as well-nourished and undernourished SCD patients in all SF-36v2 domains except MH and MCs.