Table 2.
Clinical and laboratory findings in patients with COVID-19.
| All patients(n=39) | D-dimer_L(n=30) | D-dimer_H(n=9) | p-value | |
|---|---|---|---|---|
| Characteristics | ||||
| Age(years) | 49.0(31.0–56.0) | 49.0(24.5–55.3) | 54.0(47.0–74.5) | 0.030 |
| Gender | ||||
| Male(n[%]) | 19[48.7] | 15[50.0] | 4[44.4] | 1.000 |
| Female(n[%]) | 20[51.3] | 15[50.0] | 5[55.6] | 1.000 |
| Chronic medical illness | ||||
| CVD(n[%]) | 3[7.7] | 1[3.3] | 2[22.2] | 0.127 |
| Current Smokers(n[%]) | 4[10.3] | 3[10.0] | 1[11.1] | 1.000 |
| Diabetes(n[%]) | 4[10.3] | 2[6.7] | 2[22.2] | 0.223 |
| length of stay(days) | 12.0±4.3 | 10.7±3.6 | 16.0±4.2 | 0.001 |
| CT scores on admission | 9(5–11) | 9(5–11) | 10(9–15) | 0.022 |
| Laboratory Findings | ||||
| Leucocytes(×109 /L) | 6.27(4.64–7.82) | 5.70(4.34–7.42) | 7.55(5.47–8.80) | 0.096 |
| Lymphocytes(×109 /L) | 1.16(0.84–1.68) | 1.28(1.02–1.74) | 1.04(0.59–1.42) | 0.194 |
| Neutrophils(×109 /L) | 3.52(2.91–4.44) | 3.23(1.92–4.17) | 5.20(3.66–7.19) | 0.002 |
| NLR | 2.59 (1.86–4.28) | 2.35(1.72–3.71) | 6.19(2.79–9.79) | 0.014 |
| Monocytes(×109 /L) | 0.46(0.33–0.52) | 0.46(0.35–0.51) | 0.51(0.27–0.58) | 0.920 |
| LDL-C(mmol/L) | 1.88(1.55–2.34) | 1.85(1.55–2.35) | 1.95(1.46–2.33) | 0.764 |
| Triglycerides (mmol/L) | 1.09(0.93–1.58) | 1.24(0.95–1.60) | 0.95(0.83–1.07) | 0.072 |
| Total-cholesterol(mmol/L) | 3.87±0.95 | 3.82±0.90 | 4.04±1.00 | 0.546 |
| C-reaction protein(mg/L) | 3.50(0.50–16.50) | 1.59(0.50–5.66) | 38.88(13.60–66.60) | 0.001 |
| ESR(mm/h) | 22.0(12.0–39.5) | 19.5(10.6–29.4) | 41.7(27.0–76.8) | 0.002 |
| D-dimer(mg/L) | 0.43(0.19–0.88) | 0.35(0.15–0.52) | 4.49(1.55–7.00) | 0.000 |
Data are expressed as median (IQR), mean ± standard deviation or number[%]. Between group comparisons of continuous variables were analyzed by independent sample t-tests or Mann-Whitney U-tests, and comparisons of categorical variables by chi-square tests.
Abbreviations: COVID-19=coronavirus disease 2019; CVD=cardiovascular disease; NLR= neutrophil-lymphocyte ratio; LDL-C=low-density lipoprotein cholesterol; ESR=erythrocyte sedimentation rate; NLR: neutrophil-lymphocyte ratio.