Table 3.
Knee Injury and Osteoarthritis Outcome Score (KOOS) for patients with dabigatran, nadroparin or rivaroxaban thromboprophylaxis after total knee arthroplasty. Difference between 6 weeks postsurgery and presurgery KOOS and proportion of patients with 10 points or more improvement in KOOS between 6 weeks postsurgery and presurgery
| Dabigatran | Nadroparin | Rivaroxaban | P value | |
| Pain | n=32 | n=35 | n=35 | |
| Difference between 6 weeks postsurgery and presurgery (mean±SD) | 25±26 | 19±22 | 22±23 | 0.51 |
| Patients with ≥10 points improvement postsurgery versus presurgery, n (%) | 22 (69) | 26 (74) | 27 (77) | 0.78 |
| Symptoms | n=32 | n=35 | n=35 | |
| Difference between 6 weeks postsurgery and presurgery (mean±SD) | 12±20 | 14±20 | 16±19 | 0.63 |
| Patients with ≥10 points improvement postsurgery versus presurgery, n (%) | 17 (53) | 20 (57) | 22 (63) | 0.72 |
| ADL | n=32 | n=35 | n=35 | |
| Difference between 6 weeks postsurgery and presurgery (mean±SD) | 25±20 | 23±21 | 21±17 | 0.75 |
| Patients with ≥10 points improvement postsurgery versus presurgery, n (%) | 23 (72) | 25 (71) | 27 (77) | 0.88 |
| Sport and recreation | n=29 | n=31 | n=29 | |
| Difference between 6 weeks postsurgery and presurgery (mean±SD) | 24±38 | 25±41 | 28±33 | 0.89 |
| Patients with ≥10 points improvement postsurgery versus presurgery, n (%) | 17 (59) | 21 (68) | 23 (79) | 0.24 |
| Quality of life | n=31 | n=35 | n=35 | |
| Difference between 6 weeks postsurgery and presurgery (mean±SD) | 26±27 | 18±20 | 22±21 | 0.39 |
| Patients with ≥10 points improvement postsurgery versus presurgery, n (%) | 24 (77) | 23 (66) | 23 (66) | 0.55 |
Due to the explorative nature of this pilot study, all p values are explorativerather than confirmative and are not corrected for multiple testing.
ADL, activities of daily living function.