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. 2021 Jan 14;13:367–377. doi: 10.2147/CMAR.S277399

Figure 7.

Figure 7

CYP1B1 reverses the regulation of cisplatin induced apoptosis by UCA1 or miR-513a-3p in human gastric cancer cells. (AB) CYP1B1 overexpression decreased cisplatin induced apoptosis in UCA1 knockdown NCI-N87 cells using detection of flow cytometer (A), and apoptotic cells were statistically compared (B); (C and D) CYP1B1 knockdown increased cisplatin induced apoptosis in miR-513a-3p knockdown NCI-N87 cells using detection of flow cytometer (C), and apoptotic cells were statistically compared (D). Each experiment was repeated three times independently. The rate of apoptosis cells was shown as mean ±SD, *p<0.001 vs si-UCA1 group, **p<0.001 vs inhibitor group, and the p-value was calculated by Student’s t-test.