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. Author manuscript; available in PMC: 2021 Jan 18.
Published in final edited form as: Sci Transl Med. 2020 Jul 22;12(553):eaaw0638. doi: 10.1126/scitranslmed.aaw0638

Fig. 3. VAT-resident macrophages exhibit a unique transcriptome profile.

Fig. 3.

All experiments were performed in lean C57BL/6 mice without MI. (A) Assessment of morphology of isolated blood monocytes and VAT macrophages by Wright-Giemsa staining. Scale bar, 10 μm. (B) The heatmap displays genes obtained from RNA sequencing analysis with at least twofold difference between the VAT macrophage subsets (FDR < 0.05). Principal components analysis (PCA) (C) and a Venn diagram (D) showing differentially expressed genes among monocytes and the VAT macrophage subsets. PCA plot (E) and bar graph (F) compare VAT macrophages to other tissue-resident macrophages. n = 3 per group.