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. Author manuscript; available in PMC: 2021 Jan 18.
Published in final edited form as: Sci Transl Med. 2020 Jul 22;12(553):eaaw0638. doi: 10.1126/scitranslmed.aaw0638

Fig. 4. Acute organ injuries trigger insulin resistance in non-diabetic patients and mice.

Fig. 4.

(A) Distribution of patient groups at admission in patients with ST-elevation MI (STEMI). n = 4455. (B and C) Fasting blood glucose concentrations in non-diabetic patients 15 days (average) before and 30 days after STEMI. n = 27 per group. (D) Glucose tolerance test (GTT) in lean and obese C57BL/6 mice after MI. Fasting serum insulin concentrations (E) and pAkt contents in the liver and skeletal muscle (F) in lean C57BL/6 mice at day 7 after MI. n = 6 to 7 per group. (G) GTT 7 days after BaCl2 injection. Data pooled from two independently performed experiments. Means ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001.