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. Author manuscript; available in PMC: 2021 Jan 18.
Published in final edited form as: Sci Transl Med. 2020 Jul 22;12(553):eaaw0638. doi: 10.1126/scitranslmed.aaw0638

Fig. 5. Acute injuries in distant organs result in a reduction of VAT-resident macrophages.

Fig. 5.

Quantification of VAT macrophage subsets using flow cytometry in lean C57BL/6 mice on day 7 after MI (n = 3 to 7 per group) (A), intravital microscopy in lean CX3CR1CreER/+ ROSAtdTomato/+ mice on days 7 and 60 after MI (n = 4 per group) (B), and flow cytometry in patients with STEMI (n = 4 to 5 per group) (C). Data pooled from three independent experiments. Scale bar, 7 μm. (D) Quantification of VAT macrophages after BaCl2-induced skeletal muscle injury in lean CX3CR1CreER/+ ROSAtdTomato/+ mice using intravital microscopy. n = 6 per group. Scale bar, 20 μm. (E) Chimerism in VAT macrophage subsets in lean CD45.1+ parabiont mice 1 week after MI. n = 4 pairs per group. Means ± SEM. *P < 0.05, ***P < 0.001, and ****P < 0.0001.