Table 3.

Case series comparing intraoperative ECMO and CPB during lung transplantation

Authors	Year	Groups compared	Total pts	No Support	ECMO	CPB	Postop MV	PGD at T72h	Survival/mortality	Comments
Zhang et al. [51]	2020	ECMO vs No ECMO	138	94	44	No			1-, 3-, 12-month survival ECMO 90.9%, 72.7%, 56.8% No ECMO 95.4%, 82.7%, 73.6%	Preop factors for ECMO: age, high PA, preop MV
Hashimoto et al. [52]	2018	VV ECMO vs VA ECMO	34		VV 20 VA 11	3			1-year survival VA 90%, VV 73.1% No difference
Machuca et al. [53]	2015	ECMO vs CPB	99		33	66	3 days vs 7.5 days		90-day mortality ECMO 6% vs CPB 15%	ICU, Hosp stay, and blood requirement less for ECMO
Biscotti et al. [54]	2014	ECMO vs CPB	102		47	55		ECMO 26 (56.5%) CPB 42 (76.4%)	No survival difference in 30 days or 1 year	ECMO required less transfusions and bleeding
Ius et al. [55]	2012	ECMO vs CPB	92		46	46			3-, 9-, 12-month survival CPB 70.59.56% vs ECMO 87,81,81%	ECMO less PRC, platelet intraop
Bittner et al. [56]	2007	ECMO vs CPB	47		8	7			Increased infections and mortality in ECMO	Higher blood product use in ECMO
Aigner et al. [57]	2007	ECMO vs CPB vs No Support	149		130	27			3-month, 1-year, 3-year survival ECMO 85.4%, 74.2%, 67.6% No ECMO 93.5%, 91.9%, 86.5% CPB 74%, 65.9%, 57.7%	ECMO is a valuable tool and can replace CPB