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. 2021 Jan 5;11:608976. doi: 10.3389/fimmu.2020.608976

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Copyright © 2021 Xu and Lei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Regulation of TAK1-TABs complex by different post-translational modifications. TAK1-TABs complex is modified by various post-translational modifications including acylation (Ac), methylation (Me), sumoylation (S), and O-GlcNAcylation (O), which regulates the activation and the assembly of the complex in response to different stimulation.