Table 1.
Demographic and clinical characteristics of the study group.
| Characteristic | Hypersensitivity pneumonitis (n = 75) | Avian antigen exposed controls (n = 64) | p-value | Non-exposed controls (n = 194) | p-value |
|---|---|---|---|---|---|
| Sex, male/female (%) | 5/70 (8/92) | 45/19 (70/30) | 3.4E-16 | 124/70(64/36) | 3.5E-17 |
| Age (years) | 44 ± 13.2 | 35 ± 8.8 | NS | 41 ± 14.5 | NS |
| Non-smokers/smokers (%) | 61/14 (81/19) | 57/7 (90/10) | NS | 103/91(53/47) | 0.00002 |
| FVC % predicted | 56.6 ± 21.6 | ND | 106.5 ± 11.3* | ||
| FEV1 % predicted | 59.6 ± 21.7 | ND | 99.7 ± 12.8* | ||
| FEV1/FVC% | 90.7 ± 8.5 | ND | 79.3 ± 5.5* | ||
| DLCO (n = 43) | 53.7 ± 21.4 | ND | ND | ||
| Oxygen saturation at rest (%) | 85.4 ± 8.4b | ND | ND |
ND, Not done; NS, Not significant;
*
Performed in 122 healthy non-exposed controls.
Paired t-test was done between HP vs. Avian antigen exposed controls and HP vs. Non-exposed controls.