Table 3.

Hypersensitivity Pneumonitis (HP) vs. non-exposed controls (univariate analysis).

Gene	Allele	HP		Healthy control		w/o adjusting for sex and smoking status		After adjusting for sex and smoking status
		n	MAF (%)	n	MAF (%)	OR (95% CI)	p-value	OR (95% CI)	p-value
SFTPA1	rs1059047_C	72	0.49	192	0.4	1.4 (0.8–2.4)	0.21	1.8 (0.9–3.8)	0.1
SFTPA1	rs1136450_G	72	0.65	192	0.71	0.8 (0.4–1.4)	0.38	0.5 (0.2–1.0)	0.06
SFTPA1	rs1136451_G	72	0.58	192	0.52	1.3 (0.7–2.2)	0.37	2.0 (1.0–4.1)	0.07
SFTPA1	rs1059057_G	72	0.49	192	0.4	1.4 (0.8–2.5)	0.19	2.0 (1.0–4.2)	0.06
SFTPA2	rs1059046_C	72	0.78	193	0.71	1.5 (0.8–2.8)	0.24	2.1 (0.9–4.7)	0.07
SFTPA2	rs17886395_C	72	0.5	193	0.46	1.2 (0.7–2.0)	0.57	1.9 (0.9–4.0)	0.08
SFTPB	rs1130866_T	75	0.49	194	0.68	0.5 (0.3–0.8)	0.01	0.3 (0.2–0.7)	<0.01
SFTPD	rs721917_T	75	0.73	192	0.83	0.6 (0.3–1.1)	0.08	0.3 (0.1–0.6)	<0.01
SFTPD	rs2243639_A	75	0.61	191	0.71	0.6 (0.4–1.1)	0.12	0.4 (0.2–0.9)	0.02

OR, odds ratio; CI, confidence interval; MAF, minor allele frequency.