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. 2021 Jan 18;11:1650. doi: 10.1038/s41598-021-81231-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Multivariate analysis representing immune profiles in function of BP dermal exposure and sex in adult offspring mice. (A) Sample score plot and associated loading plot on the first two PCA components resulting from all data set (without BW associated parameters) in males and females offspring mice. Each color indicated groups for each sex with 0.85% confidence level ellipse plots. (B) PLS-DA sample score plot and associated loading plot on the first two components derived from data set from all treated groups in male offspring mice (without BW associated parameters). (C) PLS-DA score plot and associated loading plot on the first two components derived from data set from all treated groups in female offspring mice (without BW associated parameters). Only loadings with correlation threshold > 0.5 were represented on the loading plots. % expl var: percentages for each first two components explained by the model. N = 5–12 offspring mice per group.