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. 2021 Jan 5;13:608355. doi: 10.3389/fnmol.2020.608355

Table 1.

Demographic and neuropsychological characteristics of the clinical sample.

ACTS AC TS NC
Number of participants (36) 11 10 6 8
Sex (M:F) 9:2 6:4 6:0 7:1
Mean age (years) 12.3 (±2.7) 13.1 (±3.1) 13.8 (±2) 12.6 (±2.6)
IQ
TIQ 79.8 (±23.3) 74.3 (±16.3) 96.3 (±11.2) 88.6 (±9.4)
VIQ 79.9 (±22.5) 74.9 (±17.2) 95.3 (±11.3) 86.2 (±9.3)
PIQ 86.7 (±21.6) 77.8 (±17.4) 98.6 (±16.4) 93.1 (±8.5)
YGTSS
Total 19.9 (±8.3) 0 22.5 (±7.2) 0
Motor 12 (±4.1) 0 13.6 (±4.7) 0
Fonic 7.9 (±5.4) 0 8.8 (±2.9) 0
CYBOCS
Total 14.4 (±5.4) 8.2 (±2.8) 18 (±9.7) 7.2 (±3.1)
Obsessions 6.5 (±2.2) 4 (±2.2) 9.3 (±4.8) 4 (±2.7)
Compulsions 7.9 (±3.4) 4.2 (±1.2) 8.6 (±5.3) 6.6 (±9.5)
CBCL
Total 54.3 (±34.4) 26.8 (±12.1) 48.1 (±15.3) 24.9 (±5.8)
Internalizing 16.6 (±11.3) 8.7 (±3.7) 11 (±3.4) 9 (±4.9)
Externalizing 21.4 (±11.9) 10.9 (±6.2) 18.5 (±6.6) 6.4 (±2.6)
Conners 29.5 (±22.3) 25.1 (±14.1) 48.1 (±15.3) 11.2 (±4.5)

Standard deviation is shown between parenthesis. ACTS, Arnold Chiari + Tourette Syndrome; AC, Arnold Chiari; TS, Tourette Syndrome; NC, Normal Control; TIQ, Total intelligence quotient; VIQ, Verbal intelligence quotient, PIQ: performance intelligence quotient; YGTSS, Yale Global Tic Severity Scale; CYBOCS Tot, Children Yale Brown Obsessive Compulsive Scale total score; CBCL-Tot, Child Behavior Check List.

According to two-tailed Mann–Whitney U test, there were no statistically significant sex differences between groups in the comparisons between TS and AC (p-value = 0.2335), TS and ACTS (p-value = 0.2952), TS and NC (p-value > 0.999), NC and AC (p-value = 0.313), NC and ACTS (p-value >0.999), AC and ACTS (p-value = 0.292) groups.