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. 2021 Jan 18;11:1687. doi: 10.1038/s41598-020-80453-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Construction of signature. (A) The risk curve in the TCGA cohort displayed the patients’ risk score, survival time, and status, and expression of stem cell-related genes. The scales represented the expression level of each gene in each sample, which was established based on z-score transformed expression data. (B) ROC curve illustrated the risk prediction of the signature for 1, 3, and 5-year in the TCGA cohort. (C) Kaplan–Meier survival revealed the overall survival among different risk stratification groups.