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. 2021 Jan 18;12(1):97. doi: 10.1038/s41419-020-03340-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A Transfection efficiency of stable MEDAG knockdown in MDA-MB-468 cells (magnification 100x). B Comparison of tumor weights in various groups (n = 4). C Representative IHC staining of EMT-related markers and Ki67 in tumors in different groups. D Protocol of the metastasis experiment. E Transfection efficiency of stable MEDAG knockdown in MDA-MB-231-luc cells (magnification 100x). F Average weight of the mice in the two groups. G Lung metastasis was detected by noninvasive bioluminescence imaging in the two groups (n = 4).