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. 2021 Jan 18;7:16. doi: 10.1038/s41420-020-00393-w

Fig. 6. AURKB inhibition triggered double-strand breaks (DSBs): Abundant expression of phospho-γH2AX (magenta), a marker of double-strand DNA breaks, in the developing buds following AURKB blockade for 24 h.

Fig. 6

Cell counting revealed extremely significant increase in the number of bud cells exposed to double-strand breaks after AURKB inhibition, analysed by paired Student’s t test at E13.5 + 24 h and E16.5+24 h (****P ≤ 0.0001, number of glands analysed ≥ 3, number of fields/group =7 – 13), scale bar = 50 µm.