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. 2021 Jan 18;7:14. doi: 10.1038/s41420-021-00403-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A The t-SNE projected three main subclones of single cells clusters from para-tumor tissues. Each cluster was labeled with Arabic number. B Heatmap of the normalized top 10 DEGs of single cells clusters in three main subclones from para-tumor tissues. C The t-SNE projected seven main subclones of single cells clusters from HCC tissues. D Heatmap of the normalized top 10 DEGs of seven main subclones in HCC tissues.