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. 2021 Jan 18;7:14. doi: 10.1038/s41420-021-00403-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A, B The transfection effect of overexpressed MLXIPL plasmids or MLXIPL siRNAs was measured by quantitative real-time PCR and western blotting. **P < 0.01; ***P < 0.001. C The proliferation ability in indicated cells was detected by the CCK8 assay after MLXIPL overexpression and knockdown separately in HCC cells. *P < 0.05; **P < 0.01; ***P < 0.001. D Apoptosis analysis in indicated cells was detected after MLXIPL overexpression and knockdown separately in HCC cells. Representative data are featured, presenting the population of living cells (Annexin V‑FITC−/PI−) in the left lower quadrant, early apoptotic cells (Annexin V‑FITC+/PI−) in right lower quadrant, late apoptotic cells (Annexin V‑FITC+/PI+) in the right upper quadrant and necrotic cells (Annexin V‑FITC−/PI+) in the left upper quadrant. ns P > 0.05; **P < 0.01; ***P < 0.001.