Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of the proposed model with previously published models.
| Model | Ion channels | Calcium buffering | Energy metabolism | Dopamine turnover | Levodopa uptake | ROS/α-syn | Apoptosis |
|---|---|---|---|---|---|---|---|
| Tello-Bravo9 | ✓ | ✗ | ✗ | ✓ | ✗ | ✗ | ✗ |
| Reed et al.12 | ✗ | ✗ | ✗ | ✓ | ✓ | ✗ | ✗ |
| Cloutier and Wellstead10 | ✗ | ✗ | ✓ | ✗ | ✗ | ✓ | ✗ |
| Francis et al.13 | ✓ | ✓ | ✗ | ✗ | ✗ | ✗ | ✗ |
| Cullen and Wong-Lin11 | * | ✗ | ✗ | ✓ | ✗ | ✗ | ✗ |
| Proposed model | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
*No ion channel dynamics but has spiking behavior (Izhikevich neuronal model51).
