Table 5.
Subgroup analyses for the predictive value of NLR in SSNHL prognosis. SMD = standard mean deviation; CI = confidence interval; NR = none reported; NLR = neutrophil-to-lymphocyte ratio; SSNHL = sudden sensorineural hearing loss.
| Categories | No. of studies | SMD (95% CI) | I2 |
|---|---|---|---|
| Total | 10 | −0.64 (-1.04, −0.24) | 87% |
| Region | |||
| Europen | 7 | −0.61 (-1.15, −0.07) | 87.3% |
| Asian | 3 | −0.73 (-1.47,0.01) | 88.8% |
| hematology analyzer | |||
| Beckman | 2 | −1.19 (-1.67, −0.71) | 0% |
| Sysmex | 4 | −0.21 (-0.83,0.41) | 90.1% |
| Others | 2 | −0.93 (-2.30,0.44) | 93.6% |
| NR | 2 | −0.88 (-2.49,0.73) | 87.0% |
| type of steroid | |||
| Prednisolone | 2 | −0.36 (-2.21,1.48) | 92.0% |
| Prednisone | 4 | −0.63 (-1.01, −0.24) | 70.6% |
| Others | 4 | −0.86 (-1.66, −0.05) | 89.9% |
| brand audiometry device | |||
| AC40 | 5 | −0.53 (-1.17,0.11) | 87.3% |
| Others | 1 | 0.04 (-0.41,0.48) | – |
| NR | 4 | −0.97 (-1.61, −0.32) | 88.0% |
| definition of “recovered" | |||
| ≥15 dB | 5 | −1.04 (-1.56, −0.52) | 83.2% |
| ≥10 dB | 4 | −0.31 (-1.05,043) | 89.0% |
| Others | 1 | −0.64 (-1.04, −0.24) | – |
| follow-up | |||
| 30days | 5 | −0.53 (-1.17,0.11) | 87.3% |
| Others | 4 | −0.95 (-1.64, −0.26) | 88.5% |
| NR | 1 | −0.08 (-0.49,0.33) | – |
| sample size | |||
| >60 | 5 | −0.11 (-0.53,0.32) | 86.6% |
| ≤60 | 5 | −1.28 (-1.66, −0.91) | 35.2% |