Table 6.
Subgroup analyses for the predictive value of PLR in SSNHL prognosis. SMD = standard mean deviation; CI = confidence interval; NR = none reported; PLR = platelet -to-lymphocyte ratio; SSNHL = sudden sensorineural hearing loss.
| Categories | No. of studies | SMD (95% CI) | I2 |
|---|---|---|---|
| Total | 7 | −0.40 (-0.77, −0.03) | 78.5% |
| Region | |||
| Europen | 5 | −0.31 (-0.86, 0.24) | 82.7% |
| Asian | 2 | −0.55 (-0.76, −0.34) | 0% |
| hematology analyzer | |||
| Sysmex | 2 | −0.10 (-0.97, 0.78) | 93.2% |
| Others | 3 | −0.77 (-1.17, −0.38) | 20.6% |
| NR | 2 | −0.35 (-1.09,0.39) | 73.6% |
| type of steroid | |||
| Prednisolone | 2 | 0.23 (-0.24, 0.70) | 22.6% |
| Prednisone | 2 | −0.30 (-0.80, 0.20) | 78.4% |
| Others | 3 | −0.88 (-1.20, −0.56) | 0% |
| brand audiometry device | |||
| AC40 | 3 | −0.27 (-1.21, 0.68) | 89.5% |
| NR | 4 | −0.47 (-0.80, −0.15) | 56.0% |
| definition of “recovered" | |||
| ≥15 dB | 5 | −0.98 (-1.43, −0.53) | 12.5% |
| Others | 2 | 0.18 (-0.20,0.55) | 40.9% |
| follow-up | |||
| 30days | 3 | −0.27 (-1.21,0.68) | 89.5% |
| Others | 3 | −0.57 (-0.77, −0.38) | 0% |
| NR | 1 | −0.02 (-0.43,0.40) | – |
| sample size | |||
| >60 | 4 | −0.29 (-0.80,0.22) | 87.80% |
| ≤60 | 3 | −0.66 (-1.05, −0.26) | 0% |