Figure 4.

Comparing structures of apo HSPD1 and the half-football complex (HSPD1₇/HSPE1₇/MgADP)

In all panels, the half-football complex is shown in gray (orange and green for neighboring subunits), and the corresponding apo HSPD1 subunit is shown in purple. Arrowheads are used to indicate the regions that show the biggest change.

(A) Rotation of the apical domain. Shown are the top (left) and side views of the domain (right). The black line is the rotation axis.

(B) Small changes near the nucleotide binding site involving Asp85.

(C) Altered position of the inter-subunit beta sheet in apo HSPD1 between subunits 1 and 7.

(D) Relative rotation of the equatorial domains in the single ring. The rotation axis is shown as black line.