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. 2021 Jan 14;15:165–173. doi: 10.2147/OPTH.S281666

Table 1.

Summary of Therapies for Dry Eye Disease22–25

Treatment Strategy Therapies
First line therapy Warm compresses, lid hygiene
Artificial tear supplements
Patient education
Modification of environment
Dietary modification
Second line therapy Tea tree oil therapy for Demodex
Punctal plugs
Moisture chamber devices
Ointment overnight
Intense pulsed light therapy
Topical corticosteroids
Topical Antibiotics
Oral secretagogues
Serum eye drops
Therapeutic contact lens options
Non-glucocorticoid immunomodulators (cyclosporine)
LFA-1 antagonist drugs (lifitegrast)
Oral tetracycline antibiotics
Oral and topical hyaluronic acid
Purinergic P2Y2 receptor agonist (diquafosol)
Amniotic membrane grafts
In office procedures Intense pulsed light therapy
Vectored thermal pulsation
Meibomian gland probing
BlephEx™