Table 3.
Positive responses based on the IFN‐γ production after Schu‐S4 stimulation measured by flow cytometry
|
Time Post‐Vaccination |
Group a | |||||||
|---|---|---|---|---|---|---|---|---|
| CD4+ T cells | CD8+ T cells | |||||||
| DVC‐LVS | USAMRIID‐LVS | DVC‐LVS | USAMRIID‐LVS | |||||
| n b /N (%) | 95% CI | n/N (%) | 95% CI | n/N (%) | 95% CI | n/N (%) | 95% CI | |
| Day 8 | 2/21 (9.5) | 1.2, 30.4 | 2/18 (11.1) | 1.4, 34.7 | 3/21 (14.3) | 3.0, 36.3 | 4/18 (22.2) | 6.4, 47.6 |
| Day 14 | 2/20 (10.0) | 1.2, 31.7 | 1/18 (5.6) | 0.1, 27.3 | 3/20 (15.0) | 3.2, 37.9 | 1/18 (5.6) | 0.1, 27.3 |
| Day 28 | 3/21 (14.3) | 3.0, 36.3 | 2/17 (11.8) | 1.5, 36.4 | 2/21 (9.5) | 1.2, 30.4 | 2/17 (11.8) | 1.5, 36.4 |
| Day 56 | 3/21 (14.3) | 3.0, 36.3 | 0/17 (0.0) | 0.0, 19.5 | 6/21 (28.6) | 11.3, 52.2 | 0/17 (0.0) | 0.0, 19.5 |
| Day 180 | 6/21 (28.6) | 11.3, 52.2 | 2/16 (12.5) | 1.6, 38.3 | 6/21 (28.6) | 11.3, 52.2 | 1/16 (6.3) | 0.2, 30.2 |
| Any (8–180) | 8/21 (38.1) | 18.1, 61.6 | 5/18 (27.8) | 9.7, 53.5 | 12/21 (57.1) | 34.0, 78.2 | 7/18 (38.9) | 17.3, 64.3 |
a
Per‐protocol population.
b
Positive criteria: (1) Visit (SCHU‐S4 [% cells] − Media [cells %]) ≥ 0.1%, (2) Visit (SCHU‐S4 [% cells] − Media [% cells]) − Baseline (SCHU‐S4 [% cells] − Media [% cells]) ≥ 0.1% and (3) P‐value < 0.01 and Visit (SCHU‐S4 [cells]) > 10.