Table 4.

Statistically significant (Spearman’s) correlations of variables and lesion size by per‐protocol population – both vaccines

Assay			Take	Number of observations	Spearman's Corr. (95%CI)	P‐value
Type	Timing	Variable
[3H]‐thymidine Assay	Day 8	Cell proliferation	Day 8	202	0.16 (0.02, 0.29)	0.023
	Day 14		Day 14	193	0.14 (0.00, 0.28)	0.047
	Day 28		Day 28	180	0.20 (0.05, 0.33)	0.008
	Day 56		Day 56	157	0.23 (0.07, 0.37)	0.004
	Peak Response		Max. Lesion Size	207	0.14 (0.01, 0.28)	0.037
MSD a	Day 14	IFN‐γ	Day 14	193	0.16 (0.02, 0.30)	0.023
	Day 56		Day 56	157	0.26 (0.11, 0.40)	0.001
	Peak Response		Max. Lesion Size	207	0.16 (0.03, 0.29)	0.018
Flow Cytometry
CD4+ T cells	Day 14	CD107a/b	Day 14	36	−0.36 (−0.62, −0.04)	0.027
	Peak Response		Max. Lesion Size	39	−0.46 (−0.68, −0.17)	0.002
	Peak Response	IFN‐γ	Max. Lesion Size	39	−0.32 (−0.58, −0.00)	0.045
CD8+ T cells	Peak Response	CD107a/b	Max. Lesion Size	39	−0.32 (−0.57, −0.00)	0.047

^aMeso scale discovery assay.