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. 2021 Jan 5;7:627848. doi: 10.3389/fmolb.2020.627848

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Copyright © 2021 Huang, Zhou, Wang, Cao, Ma, Ye and Gui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of E-cadherin inhibits the bladder cancer cell function. (A,C) The effect of light-induced E-cadherin expression on cell proliferation examined by colony-formation assay (A) and CCK-8 assay (C) under blue-light, dark, or light-dark condition in 5,637 and T24 cells. (B) The effect of light-induced E-cadherin expression on cell invasion examined by Transwell assay under blue-light, dark, or light-dark condition in 5,637 and T24 cells. (D) The effect of light-induced E-cadherin expression on cell apoptosis examined by Caspase-3/ELISA under blue-light, dark, or light-dark condition in 5,637 and T24 cells. Data are means ± SD. (n = 3, *p < 0.05, **p < 0.01, ***p < 0.001).