Figure 1.

Pituitary endocrine and cell type markers detected by single-cell RNA sequencing (scRNAseq). The normalized expression from the 85th percentile to the maximum of each gene is indicated by a gradient of light to dark red. Expression below the 85th percentile for a given gene is displayed as light blue. Pou1f1, Gh, Prl, Tshb, Lhb, Fshb, Pomc, and Pax7 are hormonal cell markers, whereas Sox2 marks stem cells. Nkx2-1, Pecam1, Co1a1, Hbb-bt, and C1qa are markers of nonhormonal cell types, and Mki67 is a marker of cell proliferation (see main text).